Vacuolating Cytotoxin Activity and Caga Gene of Helicobacter pylori Isolates from Peptic Ulcer and Non-Ulcer Dyspepsia Patients from Thailand
نویسندگان
چکیده
منابع مشابه
vacuolating cytotoxin a (vaca) gene in peptic ulcer disease and non-ulcer dyspepsia
background : vaculating cytotoxic a ( vaca ) gene is one of the multiple helicobacter pylori genotypes that produce a cytotoxin protein (vaca).this gene is a major cause of chronic peptic ulcers and gastric cancer. the aim of this study was to determine the correlation between vaca gene with peptic ulcer disease (pud) and non-ulcer dyspepsia (nud). methods : this was a case control study...
متن کاملCagA and VacAgenotypes in peptic ulcer disease and non-ulcer dyspepsia: acase-control study
Background :The cag pathogenicity island includes a number of genes, including cytotoxin-associated protein A (cagA) and vacuolatingcytotoxin (vacA) genotypes, which are associated with bacterial virulence. Although the role of cagA and vacA in the virulence of Helicobacter pylori (H. pylori) is well-established in epidemiological studies, the relationship between the cagA and vacA genotypes ...
متن کاملcagA and vacA in strains of Helicobacter pylori from ulcer and non-ulcerative dyspepsia patients
BACKGROUND The cytotoxin associated gene A (cagA), and the vacuolating cytotoxin gene A (vacA) of Helicobacter pylori have been associated to phenotypic characteristics of virulence. The objectives of this study were to detect the presence of cagA and to characterize the allelic variants of vacA in 63 strains of H. pylori isolated from colonized individuals with different clinical outcomes. M...
متن کاملPrevalence of Helicobacter pylori Infection in Patients with Peptic Ulcer Diseases and Non-Ulcer Dyspepsia
BACKGROUND Helicobacter pylori is known to be a cause of active chronic gastritis and has been proposed as an etiologic factor in the development of peptic ulcer disease, but controversy continues regarding the pathogenic importance and mechanism. We examined the prevalence of H. pylori infection in patients with peptic ulcers and non-ulcer dyspepsia. METHOD 749 patients (373 with duodenal ul...
متن کاملHistological Changes In Gastric Biopsies From Helicobacter Pylori-Infected Patients With And Without Peptic Ulcer
Background and Objective: Long period risk of gastric carcinoma in people affected with chronic Helicobacter pylori gastritis is 5 times more than normal people. Perhaps histological changes due to helicobacter pylori infection could be used for screening people at risk of gastric carcinoma and peptic ulcer. Materials and Methods: This study has been carried out as a cross...
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ژورنال
عنوان ژورنال: International Journal of Infectious Diseases
سال: 2008
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2008.05.605